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ASCP MLT(ASCP) ASCP-MLT

ASCP-MLT

Exam Code: ASCP-MLT

Exam Name: MEDICAL LABORATORY TECHNICIAN - MLT(ASCP)

Updated: Sep 03, 2026

Q & A: 562 Questions and Answers

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ASCP ASCP-MLT Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Immunology5–10%- Serologic procedures and immune diseases
- Principles of immunology
Topic 2: Urinalysis and Other Body Fluids5–10%- Microscopic analysis and disease correlation
- Physical and chemical testing
Topic 3: Microbiology15–20%- Bacteriology and mycology procedures
- Virology and parasitology testing
Topic 4: Chemistry20–25%- Electrolytes, acid-base, and toxicology
- Carbohydrates, lipids, and enzymes
Topic 5: Blood Banking15–20%- Transfusion practice and testing
- Blood group systems and immunology
- Blood products and components
Topic 6: Hematology20–25%- Physiology and disease states
- Laboratory testing and hemostasis
Topic 7: Laboratory Operations5–10%- Instrumentation and laboratory mathematics
- Quality assessment and safety

ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

Question 1

An international, nonprofit organization that establishes standards of best current practice for clinical laboratories is

A. Commission on Office Laboratory Accreditation (COLA)
B. the Joint Commission
C. Clinical Laboratory Standards Institute (CLSI)
D. Centers for Disease Control and Prevention (CDC)


Question 2

PCT usually rises within 3-6 hours of infection. CRP also increases rapidly following infection, but is not as specific for infection as PCT. A rise in CRP could also occur with SIRS. Lactic acid is usually used to detect and monitor impaired circulation and tissue oxygenation in critically ill patients.
Chemistry
Of the three laboratory tests that are listed, which has proven to be most effective for early differentiation of systemic inflammatory response syndrome (SIRS) from sepsis due to its increase following infection and higher specificity?

A. Procalcitonin (PCT)
B. Lactic acid
C. C-reactive protein (CRP)


Question 3

Valine substitutes for glutamic acid in the Beta 6 position to produce HbS.
To produce hemoglobin S, glutamic acid that is normally present in the sixth position on the beta globin chain is substituted with which of the following?

A. Cystine
B. Guanine
C. Thyamine
D. Valine


Question 4

Gamma globulin (anti-D) is given to Rh-negative mothers to prevent any D antibody production, which could cause harmful effects in future pregnancies with an Rh-positive fetus. The administered anti-D will bind fetal Rh-positive cells that may come from the fetus in vivo; therefore the mother will not produce anti-D herself, preventing sensitization.
A solution of gamma globulins containing anti-Rh (D) is given to an Rh (D) negative mother to:

A. Prevent fetal cells from initially sensitizing the mother
B. Neutralize any of the child's antibody that may have passed the placental barrier
C. Prevent greater antibody response in a previously sensitized mother
D. Neutralize any natural maternal antibodies present


Question 5

Glucagon and epinephrine promote glycogenolysis, conversion of glycogen to glucose, which increases plasma glucose.
Cortisol along with glucagon increases gluconeogenesis, formation of glucose from noncarbohydrates which also raises plasma glucose concentration.
Chem
Which of the following hormones increases plasma glucose concentration by converting glycogen to glucose?
Please select all correct answers

A. Cortisol
B. Glucagon
C. Epinephrine


Solutions:

Question 1
Answer: C
Question 2
Answer: A
Question 3
Answer: D
Question 4
Answer: A
Question 5
Answer: B,C

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