BPS Board of Pharmacy Specialties BPS-Pharmacotherapy

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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

Question #1
In a case-control study of 285 subjects with Alzheimer's dementia and 1,080 control subjects, the number of patients with dyslipidemia was recorded for each group. Among the subjects with dyslipidemia who had taken statins, the odds ratio for developing dementia was 0.29 (95%CI,
0.13-0.63). Which of the following statements can accurately be made about the relationship between the taking of statins and the development of dementia in this study?

A. Taking statins prevented development of dementia.
B. Taking statins was not associated with development of dementia.
C. Taking statins did not prevent development of dementia.
D. Taking statins was associated with a decreased risk of developing dementia.

Question #2
A 13-year-old boy who has asthma, weight 32kg, height 150cm, takes inhaled salmeterol one puff twice daily and inhaled fluticasone 2 puffs twice daily. The patient must stop participation in physical education classes after a few minutes due to shortness of breath. To allow the patient to participate longer, the most effective measure would be to add which of the following?

A. Inhaled albuterol 15 minutes before class
B. Inhaled cromolyn 30-60 minutes prior to class
C. An extra dose of inhaled fluticasone 1-2 hours before class
D. An extra dose of inhaled salmeterol 30-60 minutes before class

Question #3
A 69-year-old Woman with chronic liver disease treated with furosemide and potassium chloride for ascites and peripheral edema presents with weakness and fatigue. Her serum laboratory Values are:
* Sodium: 138 mEq/L
* Potassium: 2.6 mEq/L
* Glucose: 88 mg/dL
* BUN: 33 mg/dL
* Chloride: 101 mEq/L
* HCO3- 26 mEq/L
* Creatinine: 1.1 mg/dL
Attempts to increase her serum potassium over the next 48 hours include intravenous replacement (240 mEq over this period), without success. The current serum potassium concentration is 2.8 mEq/L. Which of the following is the most appropriate test to obtain for this patient?

A. Urinary potassium
B. Urinary sodium
C. Serum antidiuretic hormone
D. Serum magnesium

Question #4
A patient is receiving oxcarbazepine. Which is the most relevant toxicity monitoring parameter?

A. Serum potassium
B. Serum Creatinine
C. TSH
D. Serum Sodium

Question #5
A pharmacotherapy specialist is conducting a pharmacokinetic study of a drug. The pharmacokinetic profile of this drug is best described by a one-compartment model with a mean elimination rate constant of 0.173/h. The standard curve for the assay to be used covers the range of 5-40mcg/mL. Samples are collected shortly after single intravenous bolus drug administration, and at 4 and 8 hours after dosing. Preliminary analysis shows that the 4-hour sample concentration is 25 mcg/mL. In this situation, which of the following statements is correct?

A. All plasma concentrations are probably within the range of the standard curve and can be reliably measured.
B. Both the initial and 8-hour concentration points are probably outside the range of the standard curve but can be reliably quantitated by extrapolating the curve to higher and lower points.
C. Both the initial and 8-hour concentration points are probably outside the range of the standard curve and cannot be reliably measured without diluting the samples.
D. The initial plasma concentration is probably outside the range of the standard curve' it may be possible to dilute the sample and re-assay.

Solutions: